Orotic aciduria market is expected to gain market growth in the forecast period of 2021 to 2028. Data Bridge Market Research analyses the market is growing at a CAGR of 5.10% in the above-mentioned research forecast period. Rising number of birth rate and rising R&D in pharmaceutical industries among others.
High demand of new treatment options and growing awareness towards diseases symptoms and novel treatment also boost up the market growth. Moreover, increasing partnership and collaboration among market players and rising clinical trials act as opportunity for the market growth. But, side effects associated with drugs and therapies and strict regulations may hamper the global orotic aciduria market.
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Orotic aciduria is characterized as an autosomal recessive disease characterized by excessive excretion of orotic acid in urine under the presence of normal ammonia levels. This disease is caused due to deficiency of enzyme UMPS that is a bifunctional protein. This disease leads to development of megaloblastic anemia due to decrease pyrimidine synthesis. Decreased pyrimidine synthesis leads to decrease amount of nucleotide-lipid factors which are responsible for erythrocytes membrane synthesis. Orotic aciduria also leads to inhibition of DNA and RNA synthesis, which creates lethal effects.
The risk of congenital heart defects is increasing all over the world which is one of the associated symptoms of orotic aciduria, moreover the prevalence of musculosketal pain among infants is on rapid surge. The increasing number of infant patients associated with such anomalies demands effective treatment approaches and hence expected to provide market with the lucrative growth. It is also estimated that orotic aciduria market is growing with the CAGR of 5.10% in 2020.
On geographical estimation, North America accounts the largest market share due to increasing healthcare expenditure and rising healthcare awareness. Europe accounts the second largest market share due to ongoing research and development activities in pharmaceutical industry. Asia-Pacific is expected to account for the largest market share over coming years for the orotic aciduria market due to rising disposable income, rapid urbanisation and changing lifestyles.
The major players covered in the orotic aciduria market are Merck KGaA, Meteoric Biopharmaceuticals, Wellstat Therapeutics Corporation, among other domestic and global players. DBMR analysts understand competitive strengths and provide competitive analysis for each competitor separately.
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